Sodium-sodium exchange through the sodium pump: the roles of ATP and ADP.
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چکیده
منابع مشابه
Sodium channel, sodium pump, and sodium-calcium exchange activities in synaptosomal plasma membrane vesicles.
Two mechanisms of Na+ influx have been observed using synaptosomal plasma membrane vesicles purified by density gradient centrifugation from a synaptosomal hypotonic lysate. First, a 5-fold increase in uptake over basal Na+ entry occurs with 50 microM veratridine. The veratridine-dependent Na+ uptake is partially inhibited by 2 microM tetrodotoxin with an apparent time dependency of action (hal...
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Resealed human red cell ghosts containing caged ATP (Kaplan et al., 1978) and [3H]ADP were irradiated at 340 nm. The photochemical release of free ATP initiated a rapid transphosphorylation reaction (ATP:ADP exchange), a component of which is inhibited by ouabain. The reaction rate was measured by following the rate of appearance of [3H]ATP. The sodium pump-mediated ATP:ADP exchange reaction sh...
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There have been numerous efforts to formulate insulin into an oral dosage form. The major problems involved with the oral administration of insulin are acidic and enzymatic decomposition by the gastric medium, and poor absorption in the small intestine due to its macromolecular structure. This study attempted to test the enhancing ability of two absorption enhancers, sodium glycocholate (Na-G...
متن کاملThe identification of the sodium pump.
The identification of the sodium potassium pump as a Na+, K+-ATPase is described.
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1979
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1979.sp013061